Eric Oswald Selected Research

Mutagens

12/2022	The pks island: a bacterial Swiss army knife? Colibactin: beyond DNA damage and cancer.
1/2021	Insights into the acquisition of the pks island and production of colibactin in the Escherichia coli population.
1/2021	A Toxic Friend: Genotoxic and Mutagenic Activity of the Probiotic Strain Escherichia coli Nissle 1917.
1/2020	The Genotoxin Colibactin Shapes Gut Microbiota in Mice.
1/2019	The Escherichia coli colibactin resistance protein ClbS is a novel DNA binding protein that protects DNA from nucleolytic degradation.
1/2017	High iron supply inhibits the synthesis of the genotoxin colibactin by pathogenic Escherichia coli through a non-canonical Fur/RyhB-mediated pathway.
1/2017	The Food Contaminant Deoxynivalenol Exacerbates the Genotoxicity of Gut Microbiota.
3/2016	Escherichia coli ClbS is a colibactin resistance protein.
9/2015	The Genotoxin Colibactin Is a Determinant of Virulence in Escherichia coli K1 Experimental Neonatal Systemic Infection.
7/2014	The genotoxin colibactin exacerbates lymphopenia and decreases survival rate in mice infected with septicemic Escherichia coli.

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Eric Oswald Research Topics

Disease

19	Infections 01/2022 - 08/2003
11	Colorectal Neoplasms (Colorectal Cancer) 12/2021 - 01/2016
8	Neoplasms (Cancer) 12/2022 - 11/2016
6	Carcinogenesis 10/2019 - 12/2016
4	Inflammation (Inflammations) 05/2021 - 01/2017
3	Inflammatory Bowel Diseases (Inflammatory Bowel Disease) 12/2021 - 11/2012
3	Colonic Neoplasms (Colon Cancer) 01/2018 - 06/2011
3	Diarrhea 03/2005 - 03/2002
2	Colitis 05/2021 - 01/2021
2	Urinary Tract Infections (Urinary Tract Infection) 11/2016 - 03/2002
2	Sepsis (Septicemia) 09/2015 - 07/2014
2	Bacteremia 07/2014 - 12/2008
1	Crohn Disease (Crohn's Disease) 05/2021
1	Long Term Adverse Effects 01/2021
1	Cystic Fibrosis (Mucoviscidosis) 01/2019
1	Fanconi Anemia (Fanconi's Anemia) 01/2018
1	Asthma (Bronchial Asthma) 01/2018
1	Ataxia Telangiectasia (Louis Bar Syndrome) 01/2018
1	Emphysema 01/2018
1	Pneumonia (Pneumonitis) 01/2018
1	Irritable Bowel Syndrome (Syndrome, Irritable Bowel) 11/2017
1	Visceral Pain 11/2017
1	Neuroinflammatory Diseases 01/2017
1	Experimental Autoimmune Encephalomyelitis (Encephalomyelitis, Autoimmune Experimental) 01/2017
1	Anemia 01/2017
1	Genomic Instability 09/2015
1	Meningitis 09/2015
1	Hypersensitivity (Allergy) 06/2015
1	Lymphopenia (Lymphocytopenia) 07/2014
1	Leukemia 01/2013
1	Chromosomal Instability (Chromosome Stability) 06/2011
1	Prostatitis 06/2011
1	Necrosis 10/2009
1	Periodontal Diseases (Periodontal Disease) 12/2003
1	Persistent Infection 04/2003

Drug/Important Bio-Agent (IBA)

22	colibactinIBA 12/2022 - 12/2008
11	MutagensIBA 12/2022 - 06/2011
8	Virulence Factors (Pathogenicity Factors)IBA 01/2020 - 04/2003
5	DNA (Deoxyribonucleic Acid)IBA 01/2021 - 06/2011
3	Peptide Hydrolases (Proteases)FDA Link 05/2021 - 03/2002
3	PolyketidesIBA 01/2020 - 12/2008
3	Proteins (Proteins, Gene)FDA Link 01/2018 - 09/2008
3	17-hydroxyestrane-3-carbonitrile (ECN)IBA 01/2018 - 01/2017
3	IronIBA 01/2017 - 12/2016
3	cytolethal distending toxinIBA 12/2003 - 03/2002
2	Analgesics (Analgesic Drugs)IBA 01/2020 - 11/2017
2	Peptides (Polypeptides)IBA 01/2020 - 09/2015
2	Polyketide SynthasesIBA 01/2019 - 01/2016
2	Capsules (Microcapsules)IBA 09/2015 - 03/2002
2	Anti-Bacterial Agents (Antibiotics)IBA 07/2014 - 06/2011
1	Penicillin G (Benzylpenicillin)FDA LinkGeneric 01/2022
1	Cephalosporins (Cephalosporin Antibiotics)IBA 01/2022
1	Third Generation CephalosporinsIBA 01/2022
1	Mesalamine (Mesalazine)FDA LinkGeneric 12/2021
1	AcidsIBA 05/2021
1	Proteinase-Activated ReceptorsIBA 05/2021
1	Thrombin FDA Link 05/2021
1	Dabigatran FDA Link 05/2021
1	Fatty Acids (Saturated Fatty Acids)IBA 01/2021
1	EnzymesIBA 01/2021
1	Alkylating AgentsIBA 01/2021
1	Dextran SulfateIBA 01/2021
1	PolyaminesIBA 10/2019
1	SpermidineIBA 10/2019
1	tazobactam drug combination ceftolozaneIBA 01/2019
1	LactamsIBA 01/2019
1	ceftazidime drug combination avibactamIBA 01/2019
1	AllergensIBA 01/2018
1	Antineoplastic Agents (Antineoplastics)IBA 01/2018
1	PapainIBA 01/2018
1	Phosphotransferases (Kinase)IBA 01/2018
1	Fanconi Anemia Complementation Group D2 ProteinIBA 01/2018
1	Interleukin-10 (Interleukin 10)IBA 01/2017
1	HepcidinsIBA 01/2017
1	activin BIBA 01/2017
1	Ciprofloxacin (Cipro)FDA LinkGeneric 11/2016
1	Calcibiotic Root Canal SealerIBA 02/2016
1	AntigensIBA 06/2015
1	HeterochromatinIBA 01/2013
1	GalactosidasesIBA 01/2013
1	1,2- di- (4- sulfamidophenyl)- 4- butylpyrazolidine- 3,5- dione (DSB)IBA 01/2013
1	Annexin A5IBA 12/2009
1	L-Lactate Dehydrogenase (Lactate Dehydrogenase)IBA 12/2009
1	Caspase 3 (Caspase-3)IBA 12/2009
1	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 10/2009
1	NF-kappa B (NF-kB)IBA 10/2009
1	AgglutininsIBA 12/2008
1	Profilins (Profilin)IBA 09/2008
1	Wiskott-Aldrich Syndrome ProteinIBA 09/2008
1	PrebioticsIBA 05/2008
1	Phosphoric Monoester Hydrolases (Phosphatases)IBA 12/2006
1	Bacterial AdhesinsIBA 03/2005
1	CytokinesIBA 01/2005
1	Interleukin-6 (Interleukin 6)IBA 01/2005
1	VaccinesIBA 08/2003

Therapy/Procedure

4	Therapeutics 01/2021 - 01/2017
4	Oral Administration 01/2021 - 11/2012
1	Fluid Therapy (Oral Rehydration Therapy) 07/2014